The highly anticipated anime adaptation of “My Friend’s Little Sister Has It In for Me!” (also known as ImoUza!) is officially slated to premiere on October 4, 2025, in Japan. The announcement was accompanied by the release of a dynamic main promotional video, which offers a glimpse into the series’ romantic comedy antics and features previews of both its opening and ending theme songs.
Premiere Date and Broadcast Details
Fans can mark their calendars for October 4, 2025, when “My Friend’s Little Sister Has It In for Me!” will begin its broadcast. The series is set to air as part of TV Asahi’s “NUMAnimation” programming block, with its debut effectively falling on October 5 at 1:30 AM JST. Crunchyroll has confirmed the October 2025 debut, building anticipation for the light novel adaptation.
Main Trailer Highlights Love Triangle and Antics
The newly released main trailer provides an exciting look at the anime’s premise, showcasing protagonist Akiteru Oboshi as his meticulously organized daily life is turned upside down. Viewers can observe the comedic chaos that ensues as Akiteru finds himself caught between the “annoyingly cute” heroine Iroha Kohinata—his best friend’s little sister—and the aloof Mashiro Tsukinomori, who plays the role of his fake girlfriend. The visuals hint at the series’ blend of teasing, misunderstandings, and romantic comedy elements that have made the light novel popular.
Theme Songs Revealed: Opening and Ending Tracks
The trailer also provided the first listen to the anime’s vibrant theme songs. The opening theme, titled “Uza Kawaikute Naniga Warui!” (What’s Wrong With Being Annoyingly Cute!), will be performed by VTuber Akami Karubi. Meanwhile, the ending theme, “Hoshi no Kodou” (The Pulse of the Stars or Heartbeat of the Stars), is sung by Kohana Lam. Both songs are expected to complement the series’ lighthearted yet heartfelt narrative.
Key Visual and Returning Voice Cast
In addition to the trailer, a new key visual was unveiled, featuring the main cast in a lively illustration. The anime boasts a talented voice cast, many of whom are reprising their roles from the drama CD adaptation. The main cast includes:
- Haruki Ishiya as Akiteru Ooboshi
- Sayumi Suzushiro as Iroha Kohinata
- Tomori Kusunoki as Mashiro Tsukinomori
- Soma Saito as Ozuma Kohinata
- Kana Hanazawa as Sumire Kageishi
Production Staff and Source Material Insights
The television anime series is being produced by Studio BLADE. The creative team behind the adaptation includes:
- Director: Kazuomi Koga (known for Rent-A-Girlfriend and TenPuru)
- Series Composition & Scripts: Toko Machida
- Character Designs: Katsuyuki Satou
“My Friend’s Little Sister Has It In for Me!” is based on the romantic comedy light novel series written by Ghost Mikawa and illustrated by Tomari. The series, published by SB Creative under their GA Bunko imprint since April 2019, has gathered 11 volumes as of March 2025. J-Novel Club licenses the light novel in North America and describes the plot: Akiteru, disheartened by past experiences where teasing didn’t equate to affection, is focused on a career opportunity at his uncle’s business. This opportunity, however, comes with the condition that he pretend to be his uncle’s daughter’s boyfriend, leading to unpredictable interactions, especially with Iroha, his best friend’s relentlessly teasing little sister. A manga adaptation by Hira Hiraoka is also serialized on Square Enix’s Manga Up! magazine, with Comikey publishing it in English.